Tom the cat and Jerry the mouse get kicked out of their home and relocate to a fancy New York hotel, where a scrappy employee named Kayla will lose her job if she can't evict Jerry before a high-class wedding at the hotel. Her solution? Hiring Tom to get rid of the pesky mouse.

When the IMF is dissolved, Ethan Hunt and his allies launch their own war against the Syndicate, a group of renegade spies bent on world destruction.