Two Harkonnen sisters combat forces that threaten the future of humankind and establish the fabled sect that will become known as the Bene Gesserit.

In the last years of Victoria's reign, London is beset by the "Touched": people — mostly women — who suddenly manifest abnormal abilities, some charming, some very disturbing. Among them are Amalia True, a mysterious, quick-fisted widow, and Penance Adair, a brilliant young inventor. They are the champions of this new underclass, making a home for the Touched, while fighting the forces of… well, pretty much all the forces — to make room for those whom history as we know it has no place.

In the 18th century, apprentice exorcist Tom Ward is the lynchpin in a battle between good and evil when imprisoned witch Mother Malkin escapes.

A crack team of DEA agents plots a daring heist, making off with $10 million in drug money. They soon find themselves targets of an unknown killer.