American Ultra is a fast-paced action comedy about Mike, a seemingly hapless and unmotivated stoner whose small-town life with his live-in girlfriend, Phoebe, is suddenly turned upside down. Unbeknownst to him, Mike is actually a highly trained, lethal sleeper agent. In the blink of an eye, as his secret past comes back to haunt him, Mike is thrust into the middle of a deadly government operation and is forced to summon his inner action-hero in order to survive.

Russian inmate Boyka, now severely hobbled by the knee injury suffered at the end of Undisputed 2. No longer the feared prison fighter he was, he has declined so far that he is now good only for cleaning toilets. But when a new prison fight tournament begins - an international affair, matching the best fighters from prisons around the globe, enticing them with the promise of freedom for the winner - Boyka must reclaim his dignity and fight for his position in the tournament.